Endocrine Abstracts

Introduction: Hyperprolactinemia is a relatively frequent finding. A wide range of conditions can be responsible of this biochemical abnormality. Herein we report a rather rare etiology of hyperprolactinemia which is Turner syndrome (TS).Methods: Aiming to determine the frequency of hyperprolactinemia in patients with TS, we enrolled a retrospective descriptive study in the department of Endocrinology at the Hedi Chaker Hospital. We included patients who...

Introduction: Congenital Hypothyroidism is the principal cause of preventable mental retardation. It is due to Thyroid dysgenesis in 85% of the cases and in 15% to thyroid dyshormonogenesis.Methods: We conducted a prospective study including 17 patients with familial congenital hypothyroidism due to thyroid dyshormonogenesis other than the features of thyroid gland by ultrasound. Other than the phenotype we evaluated the functionality by thyroid Scintigr...

Introduction: Inappropriate glucocorticoid replacement therapy results in higher mortality rates in patients with Addison disease (AD), predominantly due to higher prevalence of cardiovascular diseases, disturbed glycometabolic state and altered anthropometric parameters. The aim of this study was to assess the impact of life-long corticosteroid exposure on anthropometric parameters in patients with AD.Patients and Methods: This Tunisian cross-sectional ...

Objective: To describe the clinical and biological presentation of acute pancreatitis (AP) and diabetic ketoacidosis (DKA) in type 1 diabetes (T1D).Patients and Methods: A retrospective descriptive study of 10 T1DM patients with simultaneous DKA and AP.Results: The mean age at diagnosis of T1DM was 19.7±9.3 years with a female predominance (60%). T1DM was frequently inaugurated by a cardinal syndrome (50%) or spontaneous DKA (20...

Objective: To assess the prevalence of obesity and metabolic disorders in patients with non-functional pituitary adenomas (NFPA)Patients and methods: A retrospective descriptive study of 35 patients followed for NFPA between 2000 and 2022. Metabolic syndrome was established according to the National Cholesterol Education Program Adult Treatment Panel III criteria.Results: The mean age was 52.1±11.4 years, with a male predomina...

Background and aims: Pituitary adenomas (PA) are small, generally benign tumors found in the pituitary gland. PA in men are rare However, they are characterized by the frequency of invasive and aggressive tumours, which makes their management difficult. The aim of this study is to clarify radiological characteristics of pituitary adenomas in men. Materials and methods: Retrospective descriptive study of 80 adult men with PA, hospitalized in the endocrinology department from 19...

Background and aim: Disorders of the development of the pituitary gland could result in some forms of Congenital Growth hormone deficiency (CGHD). This study aims to assess the morphological abnormalities of the pituitary gland in patients with CGHD.Patients and Methods: We conducted a retrospective study (1991–2019) at the Endocrinology department of Hedi Chaker University Hospital, Sfax, Tunisia. We involved 87 patients diagnosed with CGHD, whose ...

Objective: To describe the radiological features of non-functioning pituitary adenomas (NFPA) at diagnosis.Patients and methods: A retrospective descriptive study of 35 patients followed for NFPA between 2000 and 2022. A pituitary magnetic resonance imaging (MRI) scan was performed in all patients.Results: The mean age was 52.1±11.4 years with a male predominance (61.3%). Pituitary tumor syndrome was the main reason for consul...

Introduction: Prolactinomas in men are rare but are characterised by their giant and invasive nature. They present with signs of hypogonadism and mass effect. The aim of this study is to clarify the clinical, biological, radiological and therapeutic features of Prolactinomas in men.Patients and methods: Retrospective descriptive study including 27 adult males with a prolactin pituitary adenoma hospitalized in the endocrinology department of the Hedi Chak...

Background and Aim: Non-functioning pituitary adenoma (NFPA) is the second most common subtype of pituitary adenomas. This study aims to detail the clinical and biological particularities of NFPA in the Tunisian population.Patients and Methods: A retrospective descriptive study of 35 patients followed for NFPA was conducted between 2000 and 2022 at the endocrinology Department of Hedi Chaker University Hospital, Sfax, Tunisia.Resul...